Sisto Family History
Sisto Surname Meaning
Italian (mainly southern): from the personal name Sisto, a variant of Sesto. The name was popularized through the cults of various Christian popes, saints, and martyrs named Sixtus in Latin.
Galician: habitational name from any of various places in Galicia (Spain) named Sisto.
Source: Dictionary of American Family Names 2nd edition, 2022
