Mouse Family History

English: nickname from Middle English mous ‘mouse’ (Old English mūs) perhaps for a timorous person. English: perhaps also a variant of Mowe + post-medieval excrescent -s.

Mow which is found as a Bedfordshire surname may have been pronounced to rhyme with both grow and cow in post-medieval dialects. In the latter case the -s form would have become identified with the word mouse.

Americanized form of German Maus. Native American (Cherokee): from English mouse probably as a translation of a personal name or nickname based on a Cherokee name for a mouse.