Missenden Family History
Missenden Surname Meaning
From Great or Little Missenden (Bucks) recorded as Mesendena in 1154, Missend' about 1182, and Mussend' about 1200.
The place-name may derive from Old English *myssen ‘growing with mysse’ (a derivative of the plant name *mysse, the exact sense of which is unknown) + denu ‘valley’.
Alternatively, the initial element may be a lost river-name *Mysse (genitive *Myssan), probably an early name for the river Misbourne.
Source: The Concise Oxford Dictionary of Family Names in Britain, 2021
